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Updated: May 28, 2026

High-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts
Published on: December 20, 2024
Pleomorphic giant cell ductal carcinoma of the breast
D Tacchini1, M G Mastrogiulio, L Vassallo
1Department of Human Pathology and Oncology, Section of Pathology, Policlinico S. Maria Alle Scotte, University of Siena, Italy. damianatacchini@virgilio.it
Abstract:
Pleomorphic ductal invasive carcinoma is a very rare, high-grade breast cancer with unfavourable prognosis. It contains highly pleomorphic giant cells, which represent more than 50% of the cancer cells. One such case is described herein, focusing on its morphological, histopathological and immunohistochemical patterns. It was multicentric, oestrogen and progesterone receptor negative and epidermal growth factor receptor type 2 positive.
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