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Updated: May 28, 2026

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

DNA-enabled self-assembly of plasmonic nanoclusters.

Jonathan A Fan¹, Yu He, Kui Bao

¹School of Engineering and Applied Sciences, Harvard University, 9 Oxford Street, Cambridge, Massachusetts 02138, United States.

|October 20, 2011

Summary

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DNA nanotechnology enables the creation of unique plasmonic nanoparticle clusters. These DNA-guided assemblies exhibit distinct magnetic and Fano-like resonances, paving the way for novel nanostructures.

Area of Science:

Nanotechnology
Plasmonics
Biomolecular Engineering

Background:

DNA nanotechnology offers a robust platform for constructing complex nanostructures.
Plasmonic nanoparticle assemblies are crucial for manipulating electromagnetic phenomena.

Purpose of the Study:

To report the assembly of DNA-functionalized nanoparticles into heteropentamer clusters.
To investigate the electromagnetic properties of these novel clusters.

Main Methods:

Utilizing DNA to direct the self-assembly of gold nanoparticles into specific cluster geometries.
Characterizing the optical and magnetic properties of the assembled heteropentamer clusters.

Main Results:

Successfully assembled DNA-functionalized nanoparticles into heteropentamer clusters (one small, four large gold spheres).

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Observed distinct magnetic and Fano-like resonances within individual clusters.

Demonstrated the dual role of DNA as an assembler and insulating spacer.

Conclusions:

DNA-enabled assembly provides a versatile method for creating functional plasmonic heterostructures.
These heterostructures can incorporate diverse materials and DNA scaffolding for advanced applications.