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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

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Related Experiment Video

Updated: May 28, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

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[Vitamin D and pregnancy].

T Bui1, S Christin-Maitre

  • 1Endocrinologie de la Reproduction, Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, Paris, France. thao.bui@sat.aphp.fr

Annales D'Endocrinologie
|October 20, 2011
PubMed
Summary
This summary is machine-generated.

Vitamin D deficiency in pregnant women is common and linked to serious health risks for both mother and child. Current supplementation guidelines may be insufficient, necessitating further research into optimal vitamin D levels during pregnancy.

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Last Updated: May 28, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Published on: December 9, 2015

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Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Area of Science:

  • Endocrinology and Metabolism
  • Maternal-Fetal Medicine
  • Nutritional Science

Context:

  • Vitamin D is crucial for calcium-phosphorus balance and bone health, with broader roles in various tissues.
  • Vitamin D deficiency is prevalent globally among pregnant women.
  • Maternal vitamin D deficiency is associated with adverse pregnancy outcomes and neonatal complications.

Purpose:

  • To highlight the significance of vitamin D in pregnancy.
  • To underscore the inadequacy of current supplementation recommendations.
  • To emphasize the need for further research on optimal vitamin D intake during gestation.

Summary:

  • Vitamin D deficiency during pregnancy presents significant risks, including preeclampsia, gestational diabetes, and caesarean delivery.
  • Infants born to deficient mothers face risks of low birth weight, neonatal rickets, hypocalcemia, asthma, and type 1 diabetes.
  • Current vitamin D supplementation levels during pregnancy may not suffice to maintain optimal 25-hydroxyvitamin D levels (above 30 ng/ml).

Impact:

  • Highlights the critical need for effective vitamin D deficiency prevention strategies in pregnant populations.
  • Underscores the importance of optimizing vitamin D intake to mitigate maternal and neonatal health risks.
  • Calls for robust randomized controlled trials to determine adequate vitamin D dosages for pregnant women.