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Updated: May 28, 2026

Murine Left Anterior Descending (LAD) Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction
Published on: April 2, 2017
Spontaneous dissection of the LAD mimicking inferior myocardial infarction
1University Clinic, Department of Internal Medicine, University of Wuerzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany. hofmann_u2@klinik.uni-wuerzburg.de
Abstract:
The case presented here is intended to raise awareness of two uncommon coronary angiographic findings in the clinical context of acute coronary syndrome. The prevalence of patients presenting with spontaneous coronary dissection as the underlying cause of an ST-elevation myocardial infarction is low. It is typically found in women, often occurring during the peripartum period. There is some debate as to whether spontaneous dissection could also be managed conservatively without coronary intervention. As for spontaneous dissection, knowledge of a culprit lesion within the distal left anterior descending artery (LAD) causing inferior ST elevation (wrap around of the LAD) is not prevalent. Patient characteristics and treatment options are discussed on the basis of the recent literature on both clinical entities.
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