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Related Concept Videos

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

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Updated: May 28, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Oligo(glycerol) methacrylate macromonomers.

Anja Thomas1, Florian K Wolf, Holger Frey

  • 1Department of Organic Chemistry, Johannes Gutenberg-University Mainz, Mainz, Germany.

Macromolecular Rapid Communications
|October 20, 2011
PubMed
Summary
This summary is machine-generated.

Protected oligo(glycerol) methacrylate macromonomers were synthesized and polymerized. Acidic hydrolysis yielded water-soluble polyhydroxy-functional polymers, demonstrating potential for advanced material applications.

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Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
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Published on: June 8, 2016

Area of Science:

  • Polymer Chemistry
  • Materials Science

Background:

  • Developing functional polymers with tunable properties is crucial for advanced applications.
  • Oligo(glycerol) methacrylate (OGly(P)MA) macromonomers offer potential for creating biocompatible and water-soluble polymer architectures.

Purpose of the Study:

  • To synthesize linear, protected ω-methoxy oligo(glycerol) methacrylate (OGly(P)MA) macromonomers.
  • To investigate the polymerization behavior of OGly(P)MA via atom transfer radical polymerization (ATRP).
  • To explore the creation of water-soluble polyhydroxy-functional polymers through deprotection.

Main Methods:

  • Anionic ring-opening polymerization of ethoxyethyl glycidyl ether (EEGE) to synthesize macromonomers.
  • Termination with methacrylic acid anhydride to introduce methacrylate groups.
  • Atom transfer radical polymerization (ATRP) for homopolymerization and copolymerization.
  • Acidic hydrolysis to remove protecting groups and yield polyhydroxy-functional structures.

Main Results:

  • Well-defined OGly(P)MA macromonomers with controlled degrees of polymerization (DP(n) = 3-11) and low polydispersity (PDI < 1.30) were synthesized.
  • Homopolymerization via ATRP yielded graft polymers with molecular weights of 20,000-30,000 g mol(-1).
  • Acidic hydrolysis successfully deprotected the polymer chains, resulting in water-soluble polyhydroxy-functional structures.

Conclusions:

  • Linear, protected OGly(P)MA macromonomers can be effectively synthesized and polymerized.
  • The resulting polymers can be deprotected to yield water-soluble, polyhydroxy-functional materials.
  • These findings open avenues for designing novel functional polymers for various applications.