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Artificial nucleus replacement: surgical and clinical experience.

Zhong-min Zhang¹, Liang Zhao, Dong-bin Qu

¹Department of Spinal and Orthopaedic Surgery, The Third Hospital, Southern Medical University, Guangzhou, China.

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|October 20, 2011

Summary

Prosthetic disc nucleus (PDN) replacement for lumbar disc herniation offers pain relief and improved function. However, long-term results show decreased disc height and potential complications, requiring careful consideration.

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Area of Science:

Spine surgery
Biomaterials science

Background:

Lumbar disc herniation is a common cause of low back pain.
Prosthetic disc nucleus (PDN) replacement is a surgical option for treating lumbar disc herniation.

Purpose of the Study:

To evaluate the long-term clinical outcomes of prosthetic disc nucleus replacement in patients with lumbar disc herniation.

Main Methods:

Seventy-two patients with lumbar disc herniation underwent PDN implantation.
Eighty-one percent of patients completed over 48 months of follow-up.
Clinical, functional, and radiographic assessments were performed, including MRI/CT scans.

Main Results:

Significant pain relief and functional improvements were observed post-implantation.
Patients showed enhanced lumbar mobility and neurological function.
However, intervertebral disc height decreased by 18%, and complications like implant dislocation and subsidence occurred.

Conclusions:

PDN replacement can effectively increase lumbar motion and improve outcomes for lumbar disc herniation.
Long-term follow-up revealed complications and a decrease in disc height, necessitating further investigation.