Stereoselectivity for DNA threading intercalation of short binuclear ruthenium complexes

Johanna Andersson1, Per Lincoln

  • 1Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.

Summary

This study explores threading DNA intercalation by ruthenium complexes, revealing optimal stereoisomer configurations for drug development. Chirality on the non-intercalating ruthenium half dictates DNA binding specificity.

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