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Related Experiment Video

Updated: May 28, 2026

Psychophysical Tracking Method to Measure Taste Preferences in Children and Adults

Psychophysical Tracking Method to Measure Taste Preferences in Children and Adults

Published on: July 16, 2016

Sweet syndrome in children.

Lily C Uihlein¹, Heather A Brandling-Bennett, Peter A Lio

¹Harvard Combined Dermatology Residency Training Program, Boston, Massachusetts, USA.

Pediatric Dermatology

|October 21, 2011

Summary

Sweet syndrome in children often presents with atypical skin lesions, not just typical ones. While infections are common triggers, a small number of pediatric cases are linked to underlying hematologic malignancy.

Area of Science:

Dermatology
Pediatrics
Oncology

Background:

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory condition.
While typically characterized by fever and neutrophilic skin lesions, its presentation in children can vary.

Purpose of the Study:

To delineate the clinical spectrum of Sweet syndrome in pediatric patients.
To identify common and atypical clinical features, associated conditions, and disease outcomes.

Main Methods:

Retrospective case series analysis of seven pediatric patients diagnosed with Sweet syndrome over 22 years.
Detailed documentation of patient demographics, lesion characteristics, systemic symptoms, medical history, pathology, and clinical course.

Main Results:

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Fever and typical lesions were observed in most patients.
Atypical presentations, including pustules, vesicles, bullae, oral ulcers, atrophic scars, and pathergy, were frequent.
Four patients had preceding infections; two had underlying hematologic malignancies.

Conclusions:

Atypical skin manifestations are common in pediatric Sweet syndrome.
Underlying hematologic malignancy is an infrequent but significant association in children with this condition.