Related Experiment Video
Updated: May 28, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Early mental health morbidity and later smoking at age 17 years
S R Zubrick1, D Lawrence, F Mitrou
1Centre for Child Health Research, The University of Western Australia, Telethon Institute for Child Health Research, Perth, WA, Australia. steve@ichr.uwa.edu.au
Background:
We examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years.
Method:
Data were from a prospective cohort study of 2868 births of which 1064 supplied information about their current smoking at 17 years of age. The association between the onset and pattern of clinically significant mental health disorders in the child and subsequent smoking at age 17 years was estimated via multivariable logistic regression.
Results:
Relative to 17 year olds who never had an externalizing disorder, 17-year-olds who had an externalizing disorder at age 5, 8 or 14 years were, respectively, 2.0 times [95% confidence interval (CI) 1.24-3.25], 1.9 (95% CI 1.00-3.65) or 3.9 times (95% CI 1.73-8.72) more likely to be a current smoker. Children with an ongoing pattern of externalizing disorder were 3.0 times (95% CI 1.89-4.84) more likely to be smokers at the age of 17 years and those whose mothers reported daily consumption of 6-10 cigarettes at 18 weeks' gestation were 2.5 times (OR 2.46, 95% CI 1.26-4.83) more likely to report smoking at 17 years of age. Associations with early anxiety and depression in the child were not found.
Conclusions:
Current smoking in 17-year-olds may be underpinned by early emergent, and then, ongoing, externalizing disorder that commenced as young as age 5 years as well as exposure to early prenatal maternal smoking. The associations documented in adults and adolescents that link tobacco smoking and mental health are likely to be in play at these early points in development.
Related Concept Videos
Stress Prevention and Stress Management Techniques IV
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Statistical Methods for Analyzing Epidemiological Data
Factors Affecting Illness
For instance, risk factors are connected to illness, disability,...
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Conduct Disorder
