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Published on: February 24, 2023
Stevens Johnson syndrome in association with Mycoplasma pneumonia
Nitin Sadoromal Manwani1, S Balasubramanian, K Dhanalakshmi
1Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital and, CHILDS Trust Medical Research Foundation, Chennai, India. drnitin171@gmail.com
Mycoplasma pneumoniae can cause Stevens Johnson syndrome (SJS) in children. A 5-year-old girl recovered from SJS with intravenous immunoglobulin (IvIg) therapy, suggesting its potential as a treatment.
Area of Science:
- Pediatrics
- Infectious Diseases
- Dermatology
Background:
- Stevens Johnson syndrome (SJS) is a severe mucocutaneous reaction.
- Infections like Mycoplasma pneumoniae and HSV are common triggers in children in developed nations.
- Drug triggers are more prevalent in the Indian subcontinent.
Observation:
- A 5-year-old girl presented with Stevens Johnson syndrome.
- The SJS was associated with Mycoplasma pneumoniae infection.
- The patient received intravenous immunoglobulin (IvIg) therapy.
Findings:
- The patient recovered successfully following IvIg treatment.
- This case highlights Mycoplasma pneumoniae as a potential SJS trigger in pediatric patients.
- Intravenous immunoglobulin (IvIg) demonstrated therapeutic efficacy.
Implications:
- Intravenous immunoglobulin (IvIg) may be a viable alternative to glucocorticoids for SJS treatment.
- Early diagnosis and prompt treatment are crucial for favorable outcomes in pediatric SJS.
- Further research into IvIg's role in managing infectious-precipitated SJS is warranted.
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