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Updated: May 28, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Anemia-associated factors in infants born at term with normal weight
Michele Pereira Netto1, Daniela da Silva Rocha, Sylvia do Carmo Castro Franceschini
1Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.
Insights
Infant iron deficiency anemia is linked to late prenatal care, maternal iron use post-birth, parental employment, and breastfeeding duration. Addressing these factors is crucial for preventing childhood anemia.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Iron deficiency anemia is a significant global health concern in infants.
- Understanding the multifactorial etiology of infant anemia is critical for effective prevention strategies.
Purpose of the Study:
- To identify key factors contributing to the development of iron deficiency anemia in infants during their second year of life.
Main Methods:
- Cross-sectional study of 104 children in Brazil.
- Data collected via interviews, 24-hour dietary recall, and anthropometric measurements.
- Laboratory tests included blood count, ferritin, and serum retinol; statistical analysis used Poisson regression.
Main Results:
- 26% of children had anemia; 9.6% had Vitamin A deficiency.
- Anemia associated with late prenatal care, no maternal postpartum iron, paternal unemployment, prior infant iron use, and prolonged breastfeeding (>4 months).
Conclusions:
- Maternal nutrition during pregnancy and infancy plays a vital role in preventing childhood anemia.
- Interventions targeting prenatal care, postpartum maternal iron supplementation, and infant feeding practices are recommended.
Objective:
To investigate the factors involved in the genesis of infant iron deficiency anemia.
Methods:
This is a cross-sectional study, which evaluated 104 children in their second year of life who were born at term with adequate weight in Viçosa, Minas Gerais, Brazil. An interview, a 24-hour recall to parents, and anthropometric assessment were used. Laboratory exams included blood count, ferritin, and serum retinol. This study was approved by the Ethics Committee of UFMG and UFV. Statistical analyses were conducted using the Epi Info and SPSS softwares. Poisson generalized linear regression model was used to determine the association of anemia with the study variables, with results expressed as prevalence ratio.
Results:
Vitamin A deficiency and anemia were identified in 9.6% e 26% of the children, respectively. Infant anemia was associated with the date of onset of prenatal care, maternal use of iron after childbirth, paternal working status, prior use of iron by the child, and duration of breastfeeding. Thus, in the second year of life, lactating children of women who began prenatal care late and did not use iron compounds after birth, with unemployed parents, who never received iron compounds, and who were predominantly breastfed for more than four months had significantly higher prevalence of anemia.
Conclusion:
The results have demonstrated the importance of nutrition during pregnancy and infancy in the prevention of anemia in children.
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