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Updated: May 28, 2026

07:07
Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Electrochemical signal modulation in homogeneous solutions using the formation of an inclusion complex between
Toshihiro Ihara1, Tsugutoshi Wasano, Ryuta Nakatake
1Department of Applied Chemistry and Biochemistry, Kumamoto University, Kumamoto 860-8555, Japan. toshi@chem.kumamoto-u.ac.jp
Abstract:
Two DNA conjugates modified with ferrocene and β-cyclodextrin were prepared as a pair of probes that work cooperatively for DNA sensing, in which the electrochemical signal of ferrocene on one probe was significantly "quenched" by the formation of an inclusion complex with β-cyclodextrin of the other probe on the DNA templates.

