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Updated: May 28, 2026

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
[Mortality analysis in acute severe pancreatitis using objective assessment of the patient state severity and
Abstract:
The dynamics of the state severity changes and polyorgan dysfunction degree were analyzed in patients, who have died as a consequence of severe acute pancreatitis. In patients, operated on later than 14th day after the disease beginning, and not operated, lethality is caused by primary pancreatogenic polyorgan dysfunction with subsequent progressing of their state due to purulent-septic complications occurrence. The state severity and polyorgan dysfunction in patients, operated on in terms up to 6 days, is connected, possibly, with not substantiated operative-anesthesiological aggression. These data witness the possibility of the patients death prevention, while refusal from "early" operations conduction.
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Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pancreatitis II: Pathophysiology
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...