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NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose
Published on: December 30, 2025
Platinum nanoparticle modified polyaniline-functionalized boron nitride nanotubes for amperometric glucose enzyme
1Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, School of Materials Science and Engineering, Shandong University, Jinan 250061, People's Republic of China.
ACS Applied Materials & Interfaces
|October 22, 2011
Summary
A novel glucose biosensor using boron nitride nanotubes (BNNTs)-polyaniline (Pani)-platinum (Pt) hybrids offers high sensitivity and stability. This amperometric biosensor demonstrates excellent performance in harsh conditions, including acidic environments and high temperatures.
Area of Science:
- Materials Science
- Nanotechnology
- Electrochemistry
Background:
- Development of advanced biosensors is crucial for accurate glucose monitoring.
- Boron nitride nanotubes (BNNTs) offer unique properties for nanomaterial applications.
- Polyaniline (Pani) and platinum (Pt) nanoparticles can enhance electrochemical sensor performance.
Purpose of the Study:
- To develop a novel amperometric glucose biosensor using BNNTs-Pani-Pt hybrids.
- To investigate the properties and performance of the developed hybrid material for glucose detection.
- To evaluate the stability and anti-interference capabilities of the biosensor under various conditions.
Main Methods:
- Fabrication of BNNTs-Pani-Pt hybrid material.
- Decoration of Pt nanoparticles on Pani-wrapped BNNTs.
- Characterization of the hybrid material's structure and properties.
- Assembly of the amperometric glucose biosensor and electrochemical measurements.
Main Results:
- The BNNTs-Pani-Pt hybrid exhibited π interactions, enhancing water solubility.
- The glucose biosensor showed high sensitivity (19.02 mA M⁻¹ cm⁻²), a wide linear range (0.01–5.5 mM), and a low detection limit (0.18 μM).
- The biosensor demonstrated excellent stability across a pH range of 3–7 and maintained high enzyme activity at 60 °C.
Conclusions:
- The developed BNNTs-Pani-Pt hybrid biosensor is highly sensitive, stable, and reproducible.
- The unique acid and thermal stability makes it suitable for industrial and biotechnological applications under harsh conditions.
- The synergistic effects of BNNTs, Pani, and Pt contribute to the superior performance of the glucose biosensor.

