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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
Cardiovascular magnetic resonance imaging in myocarditis
Helene Childs1, Matthias G Friedrich
1Stephenson Cardiovascular MR Centre at the Libin Cardiovascular Institute of Alberta, Department of Cardiac Sciences, University of Calgary, Calgary, Canada.
Progress in Cardiovascular Diseases
|October 22, 2011
Summary
Cardiovascular magnetic resonance imaging (CMR) is the leading noninvasive method for diagnosing myocarditis. Standardized CMR criteria improve assessment, offering a promising alternative to invasive biopsy for this complex heart condition.
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Medicine
Background:
- Myocarditis diagnosis remains challenging, necessitating improved noninvasive methods.
- Cardiovascular magnetic resonance imaging (CMR) is increasingly recognized for its role in evaluating myocarditis.
- Current diagnostic tools like endomyocardial biopsy have limitations.
Purpose of the Study:
- To highlight the role of CMR in noninvasive myocarditis assessment.
- To discuss the standardized CMR criteria for myocarditis evaluation.
- To emphasize the potential of CMR as a diagnostic tool for myocarditis.
Main Methods:
- Utilizing consensus on three key CMR criteria: edema, early enhancement, and late enhancement.
- Standardizing CMR protocols for myocarditis assessment.
- Comparing CMR with endomyocardial biopsy.
Main Results:
- CMR has emerged as the leading noninvasive imaging modality for myocarditis.
- Standardized criteria (edema, early, late enhancement) enhance CMR's diagnostic utility.
- CMR shows promise as a robust, noninvasive test for myocarditis.
Conclusions:
- Standardized CMR criteria have streamlined myocarditis assessment.
- CMR offers a promising, less invasive alternative to endomyocardial biopsy.
- Further research into CMR for myocarditis is warranted to improve diagnostic certainty.
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