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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

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Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Cross-reactivity00:42

Cross-reactivity

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Related Experiment Video

Updated: May 28, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

[Multiple food allergy].

Adriana Pinheiro1, Sara Prates

  • 1Serviço de Imunoalergologia. Hospital de Dona Estefânia, Lisbon.

Acta Medica Portuguesa
|October 22, 2011
PubMed
Summary
This summary is machine-generated.

This case study highlights a child with severe atopic eczema and multiple food allergies, necessitating strict dietary changes. Managing numerous food allergies requires careful monitoring to prevent reactions and nutritional issues.

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Area of Science:

  • Pediatric Allergy and Immunology
  • Clinical Dermatology

Background:

  • Multiple food allergy presents significant challenges in pediatric populations.
  • Adverse immune responses to various foods can lead to severe clinical manifestations and restrictive diets.

Observation:

  • A 4-year-old child with severe atopic eczema experienced multiple food allergies.
  • Initial specific Immunoglobulin E (IgE) testing at 8 months indicated allergies to milk, wheat, rye, barley, gluten, soy, and egg.
  • The child had a history of anaphylaxis to cheese and aggravated atopic eczema upon wheat reintroduction.

Findings:

  • The patient maintained strict avoidance of milk, egg, wheat, gluten, barley, and rye.
  • Significant dietary restrictions were implemented to manage the multiple food allergies.

Implications:

  • Managing multiple food allergies in children demands rigorous dietary control to prevent adverse reactions and nutritional deficiencies.
  • A multidisciplinary approach is crucial for effectively managing complex pediatric food allergies and associated conditions like atopic eczema.