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[Eosinophilia in a newborn: a case of giardiasis and milk allergy]

Ana Aguiar1, Sílvia Saraiva, Margarida Pontes

  • 1Serviço de Pediatria, Hospital Pedro Hispano, Matosinhos.

Acta Medica Portuguesa
|October 22, 2011
PubMed

Insights

Giardia infection in infants can cause persistent eosinophilia and may be linked to food allergies. Early diagnosis and treatment are crucial for managing symptoms and potential complications in young children.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Allergology

Background:

  • Eosinophilia is a known response to helminth infections.
  • Emerging evidence suggests Giardia lamblia can also induce eosinophilia.
  • Giardiasis may increase the risk of food allergies in children.

Observation:

  • A premature infant presented with persistent eosinophilia, vomiting, and abdominal distention.
  • Symptoms occurred upon ingestion of non-hydrolyzed milk formula, indicating potential milk allergy.
  • Stool analysis confirmed Giardia infection alongside milk allergy (grade II/III).

Findings:

  • The infant experienced clinical improvement after treatment with metronidazole for Giardia infection.
  • The case highlights a potential association between Giardia infection and allergic conditions.
  • Persistent eosinophilia resolved with antiparasitic treatment.

Implications:

  • Underscores the significance of person-to-person transmission of Giardia, particularly in pediatric settings.
  • Suggests a possible link between Giardiasis and the development of food allergies.
  • Emphasizes the need for considering parasitic infections in cases of unexplained eosinophilia and allergies in infants.
Abstract

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