Cytology of pseudomyxoma peritonei: report of two cases arising from appendiceal cystadenomas
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1Department of Pathology, George Washington University School of Medicine, Washington, DC.
Abstract:
Pseudomyxoma peritonei is the clinical term for the diffuse deposition of mucus within the peritoneal cavity secondary to a mucinous tumor of the ovary or appendix. This gelatinous ascites, or "jelly-belly," may result in death from loss of intestinal function and intestinal obstruction caused by peritoneal implants rather than visceral invasion. Microscopic evaluation of peritoneal fluid is frequently an initial diagnostic test; however, in a search of the recent literature we were surprised to find only one case report of the cytologic features. This prompted us to report the cytologic findings in the peritoneal fluid of two cases of pseudomyxoma peritonei arising from appendiceal mucinous cystadenomas.
Insights
Pseudomyxoma peritonei, a rare condition causing mucus buildup, is often diagnosed via peritoneal fluid analysis. This study highlights key cytologic findings in two appendiceal mucinous cystadenoma cases.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Pseudomyxoma peritonei involves diffuse peritoneal mucus deposition from ovarian or appendiceal tumors.
- This condition, known as "jelly-belly," can cause fatal intestinal obstruction due to peritoneal implants.
- Current literature lacks detailed cytologic descriptions of this rare condition.