Related Experiment Video
Updated: May 28, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
Systemic venous anatomy in congenital heart disease: implications for electrophysiologic testing and catheter
Rachael Louise Cordina1, David S Celermajer, Mark A McGuire
1Royal Prince Alfred Hospital, Sydney, Australia.
Insights
Congenital heart disease patients often have abnormal systemic venous anatomy, complicating electrophysiologic testing and ablation. Pre-procedural imaging is recommended to improve procedural success rates.
Area of Science:
- Cardiology
- Electrophysiology
- Congenital Heart Disease
Background:
- Cardiac arrhythmias are a major concern in patients with congenital heart disease (CHD).
- Abnormal systemic venous anatomy is common in CHD patients, potentially complicating cardiac procedures.
- Electrophysiologic testing and interventions are frequently required in this population.
Purpose of the Study:
- To review the prevalence and characteristics of systemic venous anomalies in adult congenital heart disease patients undergoing electrophysiologic testing.
- To assess the impact of these anomalies on procedural outcomes.
Main Methods:
- Retrospective review of 80 adult congenital heart disease patients who underwent electrophysiologic studies (EPS) between January 1998 and October 2009.
- Analysis of systemic venous anatomy, identifying anomalies such as left superior vena cava and interrupted inferior vena cava.
Main Results:
- Thirteen percent (10/80) of patients had congenital systemic venous anomalies.
- Common anomalies included left superior vena cava (9%) and infrahepatic interruption of the inferior vena cava (5%).
- In 40% of cases, venous abnormalities were incidentally discovered during EPS.
Conclusions:
- Systemic venous anomalies are frequent in CHD patients and can complicate electrophysiologic testing and catheter ablation.
- Pre-procedural imaging is crucial for identifying these anomalies and facilitating successful interventions.
- Awareness of venous variations is essential for optimizing patient care in CHD.
Introduction:
Cardiac arrhythmias are a significant problem in patients with congenital heart disease. Many patients with congenital heart disease have abnormal systemic venous anatomy which can complicate electrophysiologic testing, catheter ablation and pacemaker and defibrillator implantation. We reviewed the systemic venous anatomy in a cohort of patients undergoing electrophysiologic testing and catheter ablation.
Methods And Results:
We reviewed all electrophysiologic studies performed in patients with adult congenital heart disease (n = 80) at our institution between January 1998 and October 2009. Ten patients (13%) had a congenital systemic venous anomaly. Of these, seven (9%) had a left superior vena cava and four (5%) had infrahepatic interruption of the inferior vena cava (two had both anomalies). One patient's inferior vena cava was connected to a left-sided atrium; she had right atrial isomerism. In four patients (40%), systemic venous abnormalities were discovered at the time of electrophysiologic testing.
Conclusions:
Systemic venous anomalies occur frequently in the congenital heart disease population and may complicate electrophysiologic testing and catheter ablation. Pre-procedural imaging may assist in facilitating a successful procedure.
More Related Videos
06:48Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
Published on: October 28, 2020
04:37Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development
Published on: June 16, 2023
Related Concept Videos
Cardiac Catheterization II: Right Heart Catheterization
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Cardiac Catheterization III: Left Heart Catheterization
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Cardiac Catheterization I: Pre-Procedure Overview