[A new group of anti-arrhythmia agents (the search, results and concept)]

The current status of the antiarrhythmic therapy is outlined: the main electrophysiological properties underlying the classifications of antiarrhythmic agents are presented; the principles of the search for new drugs are formulated. Using as an example the creation of a new group of antiarrhythmic agents, an attempt was made to develop the concept of the directed search for cardiotropic drugs among tricyclic nitrogen-containing systems.