Swallowing dysfunction in very low birth weight infants with oral feeding desaturation

Jang Hoon Lee1, Yun Sil Chang, Hye Soo Yoo

  • 1Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.

Insights

Swallowing dysfunction is common in very low birth weight (VLBW) infants with feeding desaturation. Infants born at or before 28 weeks gestation are at higher risk, regardless of age at discharge.

Area of Science:

  • Neonatal Medicine
  • Pediatric Gastroenterology
  • Clinical Nutrition

Background:

  • Oral feeding desaturation is a concern in very low birth weight (VLBW) infants near discharge.
  • The modified barium swallow (MBS) test is used to assess swallowing function.
  • Identifying risk factors for swallowing dysfunction in VLBW infants is crucial.

Purpose of the Study:

  • To detect swallowing dysfunction using the MBS test in VLBW infants experiencing oral feeding desaturation.
  • To identify risk factors associated with swallowing dysfunction in this vulnerable population.

Main Methods:

  • Retrospective review of 41 VLBW infants referred for MBS testing due to significant oral feeding desaturation at or after 35 weeks postmenstrual age.
  • Comparison of infants with impaired airway protection (inadequate epiglottic closure, laryngeal penetration, tracheal aspiration) versus those without.

Main Results:

  • Swallowing dysfunction was detected in 11 infants (26.8%) via MBS testing.
  • Infants with impaired airway protection had a significantly lower gestational age at birth (≤ 28 weeks).
  • Postmenstrual age at testing was similar between groups.

Conclusions:

  • Swallowing dysfunction leading to aspiration is a significant cause of oral feeding desaturation in VLBW infants.
  • Infants born at or before 28 weeks gestation require careful swallowing assessment regardless of postmenstrual age.
  • Consider swallowing dysfunction in VLBW infants born extremely preterm presenting with feeding difficulties.
Abstract

Related Concept Videos

Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Glucose Transporters01:27

Glucose Transporters

Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes: