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Updated: May 28, 2026
03:28
Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
Secular changes in the semen quality in India during the past 33 years.
Madhukar Shivajirao Dama1, Singh Rajender
1Division of Endocrinology, Central Drug Research Institute, Lucknow, U.P., India.
Journal of Andrology
|October 22, 2011
Summary
Indian men show a significant decline in sperm motility but an increase in sperm concentration over the past three decades. This study analyzed semen quality trends in healthy Indian males, revealing important shifts in reproductive health indicators.
Area of Science:
- Reproductive Health
- Andrology
- Public Health
Background:
- Global studies indicate declining semen quality over six decades.
- Limited research exists on semen quality trends within the Indian population.
Purpose of the Study:
- To investigate changes in semen quality among healthy Indian men over the last three decades.
- To analyze trends in sperm concentration and motility in a large cohort of Indian males.
Main Methods:
- Meta-analysis of published studies on semen quality in Indian men from 1978 onwards.
- Inclusion of data from 19,734 healthy Indian men without a history of infertility.
- Linear regression modeling, weighted by sample size and controlling for age, to assess parameter trends.
Main Results:
- A statistically significant decrease in sperm motility was observed.
- A significant increase in sperm concentration was identified.
- No significant changes were found in other semen parameters over the study period.
Conclusions:
- Indian men have experienced a genuine decline in sperm motility.
- There has been a concurrent increase in sperm concentration among Indian men.
- Findings align with recent research on Indian subjects, highlighting evolving reproductive health patterns.
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