Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Cancer Stem Cells and Tumor Maintenance02:40

Cancer Stem Cells and Tumor Maintenance

Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reduction in Wearable-Derived Maximal Oxygen Consumption (VO₂max) During Tamsulosin Use in an Endurance Athlete.

Cureus·2026
Same author

Urologist and radiologist contributions to variation in prostate cancer detection at fusion biopsy.

BJU international·2026
Same author

Outsmarting Metastatic Prostate Cancer: Integration of Imaging, Liquid Biopsies and Biomarkers With Artificial Intelligence.

Technology in cancer research & treatment·2026
Same author

Real-World Experience With Prostate-Specific Membrane Antigen-Positron Emission Tomography in Primary Staging and Biochemical Recurrence Settings: Data From the Michigan Urological Surgery Improvement Collaborative.

Urology practice·2026
Same author

Identification of Actionable Mutations in Metastatic Castration-Resistant Prostate Cancer Through Circulating Tumor DNA: Are We There Yet?

Current oncology (Toronto, Ont.)·2025
Same author

Reply by Authors.

The Journal of urology·2025
Same journal

Curcumin induces ferroptosis in ovarian cancer cells through the Nrf2/GPX4 regulation axis.

American journal of cancer research·2026
Same journal

microRNA-454 shows anti-angiogenic and anti-metastatic activity in pancreatic ductal adenocarcinoma by targeting LRP6 [Retraction].

American journal of cancer research·2026
Same journal

A novel integrated inflammation response score (IIRS) for predicting all-cause and cardiovascular mortality among cancer survivors.

American journal of cancer research·2026
Same journal

Erratum: IGF2BP2-modified UBE2D1 Interacts with Smad2/3 to Promote the Progression of Breast Cancer.

American journal of cancer research·2026
Same journal

Establishment and validation of a 28-day clinical outcome prediction model for acute promyelocytic leukemia based on an early platelet-coagulation factor combined transfusion strategy.

American journal of cancer research·2026
Same journal

Clinical-pathological characteristics and prognosis of elderly primary liver cancer patients.

American journal of cancer research·2026
See all related articles

Related Experiment Video

Updated: May 28, 2026

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
05:17

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

Published on: May 14, 2019

Circulating tumor cells: finding the needle in the haystack.

Xiaoning Zhe, Michael L Cher, R Daniel Bonfil

    American Journal of Cancer Research
    |October 22, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Circulating tumor cells (CTCs) in the blood indicate cancer presence and prognosis. New methods for detecting and characterizing CTCs are improving our understanding of their clinical relevance in metastatic disease.

    Keywords:
    CTCsCirculating tumor cellscell capture and enumerationdetection techniqueenrichment techniqueimmunomagnetic separation

    More Related Videos

    Capture and Release of Viable Circulating Tumor Cells from Blood
    08:10

    Capture and Release of Viable Circulating Tumor Cells from Blood

    Published on: October 28, 2016

    Characterization of Tumor Cells Using a Medical Wire for Capturing Circulating Tumor Cells: A 3D Approach Based on Immunofluorescence and DNA FISH
    10:56

    Characterization of Tumor Cells Using a Medical Wire for Capturing Circulating Tumor Cells: A 3D Approach Based on Immunofluorescence and DNA FISH

    Published on: December 21, 2017

    Related Experiment Videos

    Last Updated: May 28, 2026

    Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
    05:17

    Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

    Published on: May 14, 2019

    Capture and Release of Viable Circulating Tumor Cells from Blood
    08:10

    Capture and Release of Viable Circulating Tumor Cells from Blood

    Published on: October 28, 2016

    Characterization of Tumor Cells Using a Medical Wire for Capturing Circulating Tumor Cells: A 3D Approach Based on Immunofluorescence and DNA FISH
    10:56

    Characterization of Tumor Cells Using a Medical Wire for Capturing Circulating Tumor Cells: A 3D Approach Based on Immunofluorescence and DNA FISH

    Published on: December 21, 2017

    Area of Science:

    • Oncology
    • Molecular Biology
    • Clinical Diagnostics

    Background:

    • Circulating tumor cells (CTCs) are shed from primary and metastatic tumors into the bloodstream.
    • The presence and quantity of CTCs have emerged as significant prognostic biomarkers, especially in metastatic cancers.

    Purpose of the Study:

    • To review current and emerging techniques for isolating and characterizing CTCs.
    • To discuss the clinical significance of CTC detection and characterization in cancer management.

    Main Methods:

    • Review of existing literature on CTC isolation and characterization methodologies.
    • Analysis of recent studies investigating the clinical utility of CTC detection.

    Main Results:

    • Various methods exist for CTC isolation, with ongoing development for improved sensitivity and specificity.
    • CTC detection and characterization are increasingly linked to patient prognosis and treatment response.

    Conclusions:

    • Advanced CTC detection and characterization technologies are crucial for personalized cancer care.
    • Further research will refine CTC analysis for enhanced clinical decision-making in oncology.