Related Experiment Video
Updated: May 28, 2026
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
Sarcoid-related uveitis occurring during adalimumab therapy
Purpose:
To report the first case of sarcoid-related uveitis in a patient receiving adalimumab.
Design:
Case report.
Methods:
A 61-year-old woman with rheumatoid arthritis treated with adalimumab for 4 years presented with a 1-year history of bilateral panuveitis with venous vasculitis and peripheral multifocal choroiditis. A small papular lesion was found on her forehead, which upon biopsy showed noncaseating granulomas. No systemic involvement was observed.
Results:
An ophtalmological and clinical improvement was seen after (TNF) antagonist withdrawal plus a course of prednisone.
Conclusions:
Ophthalmologists should know that a sarcoid-like granulomatosis can develop during TNFα blockade therapy.
