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Decision support for sensible dosing in electronic prescribing systems.

J J Coleman1, U Nwulu, R E Ferner

  • 1University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. j.j.coleman@bham.ac.uk

Journal of Clinical Pharmacy and Therapeutics
|October 25, 2011
PubMed
Summary
This summary is machine-generated.

A new algorithm for dose range checking in computerized prescribing systems was developed using pharmacological data. This algorithm enhances patient safety by improving the effectiveness of clinical decision support and alerts.

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Area of Science:

  • Pharmacology
  • Health Informatics
  • Clinical Decision Support

Background:

  • Computerized prescribing systems with decision support can prevent medication errors by checking doses.
  • Existing systems lack systematic methods for incorporating dosing information.
  • Ensuring appropriate medication doses is crucial to avoid toxicity or undertreatment.

Purpose of the Study:

  • To design and test a novel algorithm for dose range checking using pharmacological data.
  • To evaluate the algorithm's feasibility for implementation in electronic prescribing systems.
  • To identify essential clinical decision support functions for optimizing prescribing safety.

Main Methods:

  • Developed an algorithm based on pharmacological principles.
  • Tested the algorithm on a subset of frequently prescribed drugs within an electronic prescribing system.
  • Refined the algorithm and identified necessary system functions for effective clinical decision support.

Main Results:

  • The final algorithm incorporates eleven broad factors.
  • The algorithm successfully accommodated 30 drug-route-form combinations during testing.
  • Several system functions crucial for comprehensive dosing decision support were identified.

Conclusions:

  • The derived dose range checking algorithm can improve clinical workflow and warning systems for enhanced patient safety.
  • This work provides a foundation for developing optimal decision support schemes for prescribing systems.