Related Experiment Video
Updated: May 28, 2026

03:20
Studying Chronic Exposure of Mice to Ultraviolet B Radiation
Published on: August 19, 2025
Vitamin D, sun, sunbeds and health
Johan Moan1, Zivile Baturaite, Asta Juzeniene
1Department of Radiation Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Ullernchausseen 70, Montebello N-0310 Oslo, Norway.
Public Health Nutrition
|October 25, 2011
Summary
The overall health benefits of vitamin D may outweigh the risks of skin cancer from sensible sun exposure. This review examines UV radiation, sunbeds, and vitamin D
Area of Science:
- Dermatology
- Public Health
- Endocrinology
Background:
- Ultraviolet (UV) radiation from sun exposure and artificial sources like sunbeds is a primary source of vitamin D.
- Low vitamin D levels are prevalent, particularly among fair-skinned young populations in northern latitudes.
- Sufficient vitamin D status is linked to numerous health benefits.
Purpose of the Study:
- To review the health effects of solar radiation, sunbeds, and vitamin D.
- To evaluate the association between UV exposure, vitamin D status, and the risk of cutaneous malignant melanoma (CMM).
Main Methods:
- Literature search of MEDLINE database for studies published between 1981 and 2011.
- Inclusion of studies reporting relative risk for CMM associated with sunbed use, vitamin D, and UV effects.
- Analysis of data from diverse populations across different latitudes and age groups.
Main Results:
- UV radiation is the main source of vitamin D, essential for health.
- Despite identified health benefits, UV exposure is linked to an increased risk of CMM.
- Young individuals with lighter or pigmented skin in Northern Europe often exhibit insufficient vitamin D levels.
Conclusions:
- The health benefits of achieving adequate vitamin D levels may surpass the potential increase in CMM risk from moderate UV exposure.
- Careful consideration of UV exposure is recommended, balancing vitamin D sufficiency with skin cancer risk.
- Scientific evidence supports the assessment of overall health benefits versus CMM risk.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Mutations
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Mutations
Overview
Role of Vitamins in Maintaining Bone Health
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...

