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Related Experiment Video

Updated: May 28, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Paediatric interstitial lung disease: classification and definitions.

Megan K Dishop¹

¹Department of Pathology, The Children's Hospital, University of Colorado-Denver, USA. dishop.megan@tchden.org

Paediatric Respiratory Reviews

|October 25, 2011

Summary

This summary is machine-generated.

Recent revisions in interstitial lung disease classifications for children are reviewed, introducing a new clinicopathologic framework. This updated terminology aims to improve diagnosis and guide targeted therapies for pediatric diffuse lung diseases.

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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Area of Science:

Pediatric Pulmonology
Histopathology
Rare Lung Diseases

Background:

Classifications for interstitial (diffuse) lung disease (ILD) in children have evolved significantly.
Advances in understanding new entities, biology, and prognostic significance of histologic patterns have driven these revisions.
The European Respiratory Society Task Force and North American Children's Interstitial Lung Disease Group have made key contributions.

Purpose of the Study:

To review recent revisions in pediatric interstitial lung disease classifications.
To summarize a clinicopathologic classification of paediatric diffuse lung disease.
To present clinical characteristics and histologic definitions for specific entities.

Main Methods:

Review of contributions from the European Respiratory Society Task Force on Interstitial Lung Disease in Children.
Review of contributions from the North American Children's Interstitial Lung Disease Group.
Summarization of a clinicopathologic classification for paediatric diffuse lung disease.

Main Results:

A comprehensive clinicopathologic classification of paediatric diffuse lung disease is presented.
Clinical characteristics and histologic definitions are provided for selected entities including acinar dysgenesis, congenital alveolar dysplasia, and neuroendocrine cell hyperplasia of infancy.
The classification encompasses a range of conditions such as surfactant dysfunction disorders, obliterative bronchiolitis, and immunologic disorders.

Conclusions:

Uniform application of revised diagnostic terminology is crucial for future research.
Standardized terminology will enable more meaningful comparisons of patient populations.
This will facilitate improved radiologic-pathologic correlation and the development of disease-specific therapeutic strategies for pediatric diffuse lung diseases.