Failure to diagnose herniated discs in a depressed 43-year-old woman

Michael S Hanau1

  • 1Harvard Medical School, Boston, MA 02114, USA. mhanau@partners.org

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The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
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