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Published on: August 7, 2017
Risk of acute otitis media in relation to acute bronchiolitis in children
Mohammed A Gomaa1, Osama Galal, Mahmoud S Mahmoud
1Department of Otorhinolaryngology, Faculty of Medicine, Minia University, Egypt. magomaa@yahoo.com
Insights
Bacterial acute otitis media (AOM) is a common complication in children with acute bronchiolitis. Streptococcus pneumoniae and Haemophilus influenza were the most frequent pathogens identified.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Background:
- Acute bronchiolitis is a common respiratory infection in infants and young children.
- Acute otitis media (AOM) frequently co-occurs with acute bronchiolitis, necessitating further investigation into their relationship.
- Understanding the etiology of AOM in this context is crucial for effective management.
Purpose of the Study:
- To determine the prevalence and causes of AOM in children diagnosed with acute bronchiolitis.
- To investigate the co-occurrence of other pathogens, specifically Respiratory Syncytial Virus (RSV), in children with AOM and acute bronchiolitis.
Main Methods:
- A prospective study included 180 children aged 3-18 months with acute bronchiolitis.
- Middle-ear aspirates were analyzed using Gram staining, bacterial cultures, and ELISA for RSV detection in patients with or developing AOM.
- Analysis focused on pathogens present at the time of AOM diagnosis or within 14 days of bronchiolitis onset.
Main Results:
- AOM was present in 55.6% of children with acute bronchiolitis.
- Bacterial pathogens were isolated in 86% of middle-ear aspirates, with 49% showing mixed bacterial and RSV infections.
- RSV was detected in 56% of middle-ear aspirates, often concurrently with bacteria.
Conclusions:
- Bacterial AOM is a significant complication in the majority of children with acute bronchiolitis.
- Streptococcus pneumoniae and Haemophilus influenza were the most frequently isolated bacteria.
- RSV is a common finding in children experiencing AOM alongside acute bronchiolitis.
Objective:
A prospective study was carried out to evaluate the prevalence and the etiology of acute otitis media (AOM) in children with acute bronchiolitis. Also to determine whether AOM occurring with acute bronchiolitis is accompanied with another pathogens or not.
Subjects And Methods:
One hundred and eighty children with acute bronchiolitis aged 3-18 months who were admitted to pediatrics department, Minia University hospital, were included in the study done in the winter and spring of 2009. In patients with AOM at entry or developed AOM within 14 days, Gram-stained smears, bacterial cultures, and enzyme-linked immunosorbent assay (ELISA) were performed on middle-ear aspirates to detect the presence of bacterial pathogens and RSV respectively.
Results:
One hundred children (55.6%) with acute bronchiolitis had AOM at entry or developed AOM within 14 days, 45 patients (25%) had developed otitis media with effusion, and only 35 patients (19.4%) remained free throughout the 2-week observation period. Of 135 middle-ear aspirates (65 unilateral and 35 bilateral), bacterial pathogens were isolated in 86 patients (86%) [37 bacteria alone "37%" and 49 mixed bacteria and RSV "49%"], RSV was identified in 56 patients (56%) of middle ear aspirates [mixed with bacteria in 49 patients and RSV alone in 7 cases (7%).
Conclusion:
We concluded that bacterial AOM is a complication in most children with acute bronchiolitis. Streptococcus pneumonia and Haemophilus influenza were the commonest organisms isolated from middle ear aspirate. RSV is identified in 56% of acute otitis media with bronchiolitis.
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