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Related Concept Videos

Cellular Injury IV: Necrosis01:16

Cellular Injury IV: Necrosis

Necrosis is a form of irreversible cell death caused by severe injury such as ischemia, toxins, or trauma. Unlike programmed cell death, it is an uncontrolled, pathological process that typically provokes inflammation in surrounding tissues.Pathophysiologic ChangesNecrosis begins when cells sustain critical damage, leading to swelling of organelles, particularly mitochondria, and rapid ATP depletion. As energy levels decline, membrane ion pumps fail, leading to calcium influx and eventually,...
Necrosis01:16

Necrosis

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

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Updated: May 28, 2026

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle
09:19

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle

Published on: May 26, 2022

[Intraabdominal fat necrosis].

J J Aguilar-García1, P Alcaide-León, B Vargas-Serrano

  • 1Unidad de Gestión Clínica de Radiodiagnóstico, HH.UU. Virgen del Rocío, Sevilla, España. jjag96@hotmail.com

Radiologia
|October 25, 2011
PubMed
Summary
This summary is machine-generated.

Intraabdominal fat necrosis causes abdominal pain and can mimic other conditions. Imaging, particularly computed tomography, is crucial for accurate diagnosis and avoiding unnecessary surgery.

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Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
10:37

Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration

Published on: June 9, 2023

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Last Updated: May 28, 2026

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle
09:19

A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle

Published on: May 26, 2022

Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
10:37

Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration

Published on: June 9, 2023

Area of Science:

  • Gastroenterology
  • Radiology
  • Abdominal Imaging

Background:

  • Intraabdominal fat necrosis presents with acute or subacute abdominal pain.
  • Differential diagnoses include epiploic appendagitis, omental infarction, mesenteric panniculitis, appendicitis, diverticulitis, and neoplasms.
  • Clinical presentation alone may not suffice for accurate diagnosis, risking unnecessary surgical intervention.

Purpose of the Study:

  • To highlight the importance of imaging in diagnosing intraabdominal fat necrosis.
  • To differentiate intraabdominal fat necrosis from other causes of abdominal pain.
  • To guide radiologists in identifying characteristic imaging findings.

Main Methods:

  • Review of imaging findings in intraabdominal fat necrosis.
  • Comparison with imaging characteristics of differential diagnoses.
  • Emphasis on computed tomography (CT) and ultrasonography.

Main Results:

  • Computed tomography is essential for diagnosing intraabdominal fat necrosis.
  • Characteristic imaging findings can distinguish fat necrosis from other conditions.
  • Ultrasonography can also play a role in diagnosis.

Conclusions:

  • Accurate radiologic interpretation is vital for managing intraabdominal fat necrosis.
  • Familiarity with imaging findings prevents misdiagnosis and unnecessary surgery.
  • Timely and correct diagnosis ensures appropriate patient management.