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06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Cerebrovascular disease in 48 countries: secular trends in mortality 1950-2005
Masoud Mirzaei1, A Stewart Truswell, Kathryn Arnett
1Yazd Cardiovascular Research Centre, Afshar Hospital, Yazd, Iran. masoud.mirzaei@sydney.edu.au
Journal of Neurology, Neurosurgery, and Psychiatry
|October 25, 2011
Summary
Stroke mortality has significantly decreased globally between 1950 and 2005. Different patterns of decline suggest varying success of prevention strategies, offering insights for stroke control policies.
Area of Science:
- Epidemiology
- Public Health
- Cardiovascular Disease Research
Background:
- Stroke remains a leading cause of death and disability worldwide.
- Understanding global stroke mortality trends is crucial for public health initiatives.
Purpose of the Study:
- To investigate patterns of increase and decrease in stroke mortality across 48 countries.
- To analyze temporal trends in stroke death rates from 1950 to 2005.
Main Methods:
- Utilized age-standardized death rates (35-74 years) from the World Health Organization (WHO).
- Examined annual mortality data for 48 countries between 1950 and 2005.
- Classified countries based on stroke mortality magnitude, pattern (declining, rise and fall, rising, flat), and timing, analyzing male and female trends separately.
Main Results:
- Significant variations in secular stroke mortality trends were observed among countries.
- Identified distinct patterns: 'declining', 'rise and fall', 'rising', and 'flat' mortality.
- Noted higher epidemic peaks in Asia (e.g., Japan, Russian Federation, Bulgaria) and lower rates in Canada and Australia.
Conclusions:
- Stroke mortality substantially decreased in many countries from 1950 to 2005.
- Divergent timing of mortality decline suggests varied implementation of prevention strategies.
- Findings can inform policy interventions for stroke control, particularly in regions with rising trends.
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