Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Physiology of the Genitourinary System III: Urine Concentration and Dilution01:20

Physiology of the Genitourinary System III: Urine Concentration and Dilution

The kidneys concentrate or dilute urine to maintain water and electrolyte balance. Nephrons, particularly the loop of Henle, play a crucial role in this process through the countercurrent multiplication system. This system establishes a high osmolarity in the renal medulla, which is essential for water reabsorption. In the loop of Henle’s descending limb, water is reabsorbed into the surrounding medulla due to its permeability to water. In contrast, the ascending limb actively transports...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hormonal Regulation of Blood Pressure01:17

Hormonal Regulation of Blood Pressure

Endocrinal or hormonal intervention in the cardiovascular system is predominantly exerted by the catecholamines - epinephrine and norepinephrine, as well as a slew of hormones that interact with renal function to modulate blood volume.
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction while...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Injection of Tranexamic Acid Alone is Not Effective in Reducing Transfusion Requirements Following Total Joint Arthroplasty.

Journal of clinical practice and research·2026
Same author

Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial.

British journal of anaesthesia·2026
Same author

Multidrug-resistant colonization in decompensated cirrhosis outside the ICU predicts infection and poor outcomes.

JHEP reports : innovation in hepatology·2026
Same author

Acute normovolaemic haemodilution after cardiac surgery: a meta-analysis of randomised controlled trials.

British journal of anaesthesia·2026
Same author

Diabetes does not modify the renal-protective effect of intravenous amino acids infusion after cardiac surgery.

Journal of endocrinological investigation·2026
Same author

Duodenoduodenostomy as an Attractive Option for Exocrine Drainage in Pancreas Transplantation: Insights From a Single-Center Cohort.

Transplant international : official journal of the European Society for Organ Transplantation·2025

Related Experiment Video

Updated: May 28, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

Acute normovolemic hemodilution.

Giorgio Oriani1, Marco Pavesi, Alessandro Oriani

  • 1Servizio Anestesia ICSS, Milano, Italy. giorgio.oriani@grupposandonato.it

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|October 25, 2011
PubMed
Summary
This summary is machine-generated.

Acute normovolemic hemodilution (AHN), a blood-saving technique, is underutilized. This study explores AHN physiology and clinical application, offering tools for its safe and effective implementation to reduce blood transfusions.

More Related Videos

Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

Related Experiment Videos

Last Updated: May 28, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

Area of Science:

  • Anesthesiology and Perioperative Medicine
  • Transfusion Medicine
  • Surgical Blood Conservation

Background:

  • Acute normovolemic hemodilution (AHN) is a recognized but infrequently employed blood conservation strategy.
  • Understanding the physiological basis of low hematocrit states is crucial for effective AHN.
  • Limited clinical adoption may stem from a perceived complexity or lack of practical guidance.

Purpose of the Study:

  • To elucidate the concepts and physiological underpinnings of AHN.
  • To present clinical experience demonstrating the utility and cost-effectiveness of AHN.
  • To provide practical tools and guidelines for the safe and appropriate application of AHN.

Main Methods:

  • Review of "low hematocrit" physiology relevant to AHN.
  • Analysis of clinical experience with AHN procedures.
  • Development of practical tools for AHN decision-making and execution.

Main Results:

  • AHN is a useful and affordable method for blood saving.
  • Clinical experience supports the feasibility and benefits of AHN.
  • Proposed tools facilitate the determination of when, if, and how to apply AHN.

Conclusions:

  • AHN is an underutilized but valuable blood conservation technique.
  • This work provides a framework for understanding and implementing AHN.
  • Simple, evidence-based methods are presented to guide the safe application of AHN.