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Related Concept Videos

Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...

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Related Experiment Video

Updated: May 28, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
05:41

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions

Published on: February 9, 2024

Thyroid diseases in elderly.

A Faggiano1, M Del Prete, F Marciello

  • 1National Cancer Institute, Fondazione G. Pascale, Federico II University, Naples, Italy. afaggian@unina.it

Minerva Endocrinologica
|October 25, 2011
PubMed
Summary
This summary is machine-generated.

Thyroid diseases are common in the elderly, with unique diagnostic challenges and drug-induced alterations. Careful management and monitoring are essential for optimal treatment outcomes in older adults.

Related Experiment Videos

Last Updated: May 28, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
05:41

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions

Published on: February 9, 2024

Area of Science:

  • Endocrinology
  • Geriatrics

Background:

  • Thyroid diseases are prevalent endocrine disorders, particularly in the elderly.
  • Benign conditions are common, but age increases the risk of specific issues like toxic multinodular goiter and hypothyroidism.
  • Medications frequently impact thyroid function in older adults.

Purpose of the Study:

  • To highlight the unique aspects of thyroid disease in the elderly.
  • To emphasize the diagnostic challenges and the influence of medications.
  • To outline appropriate diagnostic and therapeutic strategies for this population.

Main Methods:

  • Comprehensive review of thyroid disease characteristics in the elderly.
  • Analysis of medication effects on thyroid function.
  • Evaluation of diagnostic and treatment approaches.

Main Results:

  • Thyroid disease prevalence and presentation differ in the elderly, with nuanced symptoms complicating diagnosis.
  • Numerous medications can suppress TSH, alter hormone levels, or cause thyrotoxicosis/hypothyroidism.
  • Aggressive thyroid cancer subtypes are more frequent in older individuals.

Conclusions:

  • Thyroid diseases in the elderly require specialized attention due to altered prevalence, diagnostic difficulties, and therapeutic constraints.
  • Medication-induced thyroid dysfunction is a significant concern, necessitating careful management and monitoring.
  • A gradual therapeutic approach with close follow-up is recommended for elderly patients requiring thyroid treatment.