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Updated: May 28, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Surgical chances in kidney cancer bone metastases]
1Dirigente Centro di Oncologia Ortopedica, 1° Ortopedia e Unità Sarcomi, Spedali Civili di Brescia, Italy.
Abstract:
Kidney cancer, together with breast and lung, is one of the most frequent primaries causing bone mestastases which require some kind of surgical treatment. Renal mets, however, have distinguished features making their surgical treatment a real challenge: their open treatment is at high risk for massive bleeding and the severe destruction of bone-stock makes reconstruction often very difficult. Nevertheless, the surgical treatment of these metastases can dramatically improve the patient's quality of life. For the important problems which must be faced and solved, surgery of Renal Cell metastases should not be left to general orthopedic surgeons but these patients should be referred to Centers with a major experience in MusculoSkeletal Oncology.
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