MRI findings of Aspergillus spondylitis

Jong Won Kwon1, Sung Hwan Hong, Sang-Hee Choi

  • 1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Abstract

Insights

Aspergillus spondylitis, a fungal infection of the spine, often presents with multiple affected disk levels and skip lesions on MRI. Key MRI findings include serrated vertebral endplates and subchondral T2 hypointensity.

Area of Science:

  • Medical Imaging
  • Infectious Diseases
  • Spinal Disorders

Background:

  • Aspergillus spondylitis is a rare but serious spinal infection.
  • Accurate diagnosis is crucial for effective treatment and patient outcomes.

Purpose of the Study:

  • To describe the characteristic magnetic resonance imaging (MRI) findings in biopsy-proven cases of Aspergillus spondylitis.
  • To aid clinicians in suspecting and diagnosing this condition based on imaging features.

Main Methods:

  • Retrospective analysis of MRI scans from patients with confirmed Aspergillus spondylitis.
  • Correlation of imaging findings with histopathological confirmation.

Main Results:

  • Aspergillus spondylitis frequently involves multiple vertebral disk levels.
  • Characteristic MRI findings include skip lesions and subligamentous spread.
  • Serrated vertebral endplate margins and subchondral T2 hypointensity are suggestive features.

Conclusions:

  • Aspergillus spondylitis diagnosis should be considered with specific MRI patterns.
  • The presence of skip lesions, subligamentous spread, serrated endplates, and T2 hypointensity are key indicators.
  • Early recognition through MRI can improve management of Aspergillus spondylitis.