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Multiple Aspergillus cerebellar abscesses in a middle-aged female: case report and literature review

Sheng Chen1, Jia-Li Pu, Jun Yu

  • 1Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

International Journal of Medical Sciences
|October 25, 2011
PubMed

Insights

Multiple Aspergillus cerebellar abscesses, a rare condition, were observed in a patient post-surgery and antibiotic treatment. Successful management involved surgical removal and voriconazole, offering a potential treatment strategy for this unusual presentation.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Cerebellar abscesses caused by Aspergillus are exceptionally rare.
  • Solitary lesions are the typical presentation of Aspergillus cerebellar infections.

Observation:

  • A 46-year-old female developed multiple Aspergillus cerebellar abscesses.
  • The patient had a history of one mastoidectomy, two craniectomies, and prolonged antibiotic therapy.

Findings:

  • This case represents the first documented instance of multiple Aspergillus cerebellar abscesses.
  • The pathogenesis of this rare multifocal infection is explored.

Implications:

  • A combination of neurosurgical resection and voriconazole (VRC) administration led to a favorable outcome.
  • This combined approach is proposed as a potential management plan for similar rare cases.
Keywords:
AspergillusCerebellumNeurosurgical resectionVoriconazole

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