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Magnetic resonance contrast media: principles and progress.

R B Lauffer1

  • 1Department of Radiology, Harvard Medical School, Boston, Massachusetts.

Magnetic Resonance Quarterly
|April 1, 1990
PubMed
Summary

This review covers magnetic resonance (MR) imaging contrast media, detailing paramagnetic and superparamagnetic agents. It explores their impact on MR relaxation, image intensity, and crucial chemical and physiological characteristics.

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Area of Science:

  • Radiology and Medical Imaging
  • Biomedical Engineering
  • Materials Science

Background:

  • Magnetic Resonance (MR) imaging is a vital diagnostic tool.
  • Contrast media significantly enhance MR imaging utility.
  • Understanding contrast agent properties is crucial for optimal imaging.

Purpose of the Study:

  • To review the principles of MR imaging contrast media.
  • To present the current state of the art in MR contrast agents.
  • To cover paramagnetic and superparamagnetic contrast agents.

Main Methods:

  • Comprehensive literature review on MR contrast agents.
  • Analysis of paramagnetic and superparamagnetic agent properties.
  • Discussion of effects on MR relaxation and image intensity.

Main Results:

  • Detailed overview of existing MR contrast media.
  • Explanation of how agents affect MR relaxation times (T1 and T2).
  • Assessment of factors influencing image intensity changes.

Conclusions:

  • Paramagnetic and superparamagnetic agents are key in MR imaging.
  • Chemical and physiological properties dictate agent performance.
  • Current advancements aim to improve safety and efficacy.

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