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Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

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Published on: April 11, 2025

Electromechanical wave imaging for arrhythmias.

Jean Provost¹, Vu Thanh-Hieu Nguyen, Diégo Legrand

¹Department of Biomedical Engineering, Columbia University, New York, NY, USA.

Physics in Medicine and Biology

|October 26, 2011

Summary

Electromechanical wave imaging (EWI) now maps heart electrical activity in a single heartbeat. This novel ultrasound technique enables real-time imaging of electromechanical waves (EW) for diagnosing arrhythmias.

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Published on: September 13, 2011

Area of Science:

Cardiovascular Imaging
Biomedical Engineering
Medical Ultrasound

Background:

Electromechanical wave imaging (EWI) maps electromechanical waves (EW), transient deformations from electrical activation.
Previous EWI methods required multiple cardiac cycles, limiting use for non-periodic arrhythmias like fibrillation.
Accurate mapping of EW is crucial for understanding cardiac electrical activity and arrhythmias.

Purpose of the Study:

To develop and validate novel, high-frame-rate EWI sequences for single-heartbeat imaging.
To assess the feasibility of EWI for characterizing non-periodic arrhythmias in a clinical-like setting.
To enable EWI application for conditions beyond regular heart rhythms.

Main Methods:

Developed new flash- and wide-beam emission imaging sequences for high frame rates (2000 fps).
Imaged the entire heart in a single heartbeat during free breathing.
Validated methods in open-chest canines against electrode measurements and assessed feasibility in closed-chest canines during various rhythms.

Main Results:

Successfully imaged electromechanical waves (EW) in a single heartbeat at 2000 fps.
Validated EW imaging against direct electrical measurements in open-chest canine models.
Demonstrated feasibility of EWI for non-periodic rhythms, including right-ventricular pacing, in closed-chest canines.

Conclusions:

Novel EWI sequences enable high-frame-rate, single-heartbeat imaging of electromechanical waves (EW).
This advancement allows characterization of non-periodic arrhythmias under free-breathing conditions.
EWI is now applicable to clinical scenarios involving arrhythmias, significantly expanding its diagnostic potential.