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Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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[Pharmacokinetics and impaired organic functions]

Etienne Chatelut1

  • 1Université de Toulouse, institut Claudius-Regaud, France. Chatelut.Etienne@claudiusregaud.fr

Bulletin Du Cancer
|October 26, 2011
PubMed
Summary

Interindividual variability in drug pharmacokinetics affects anticancer drug efficacy and toxicity. Impaired liver or kidney function significantly alters drug levels, impacting treatment outcomes.

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