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Updated: May 28, 2026
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Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
[Fetal tricuspid regurgitation].
J Pavlícek1, T Gruszka, D Matura
1Oddelení detské a prenatální kardiologie FN Ostrava. jan.pavlicek@fno.cz
Ceska Gynekologie
|October 27, 2011
Summary
Fetal tricuspid insufficiency (TI) is detectable via echocardiography and often insignificant. When TI is linked to congenital heart defects (CHDs), it may require further monitoring but typically does not predict other pathologies.
Area of Science:
- Cardiology
- Fetal Medicine
- Pediatric Cardiology
Background:
- Fetal tricuspid insufficiency (TI), or tricuspid regurgitation (TR), is a condition that can be detected during pregnancy.
- Understanding the incidence and significance of fetal TI is crucial for identifying potential congenital heart defects (CHDs) and other fetal circulatory issues.
Purpose of the Study:
- To determine the incidence and significance of fetal tricuspid insufficiency (TI).
- To evaluate the occurrence of TI in both physiologically normal fetuses and those with CHDs.
- To assess the potential of fetal TR to predict other significant heart or circulatory pathologies.
Main Methods:
- Fetal echocardiography was performed on 8,896 pregnancies between 2006 and 2010.
- Measurements of the right heart structures were taken for fetuses with and without TI.
- Fetuses diagnosed with TI underwent monitoring during pregnancy and examination after birth.
Main Results:
- Tricuspid regurgitation (TR) was identified in 2% (178) of fetuses, with 11% (20) having associated CHDs or arrhythmias.
- The majority of TI cases (89%) were insignificant.
- Parameters of the right heart in fetuses with TI did not significantly differ from those with normal tricuspid valves; no CHDs or chromosomal abnormalities were confirmed postnatally.
Conclusions:
- Fetal TI is detectable through prenatal echocardiography.
- While TI can be associated with CHDs, it is often insignificant and does not predict adverse hemodynamic outcomes or other pathologies once CHDs are ruled out.
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