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Related Concept Videos

Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...

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Optical Control of Living Cells Electrical Activity by Conjugated Polymers
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Polymers interfacing with biology.

Frederik Wurm1, Harm-Anton Klok

  • 1Ecole Polytechnique Fédérale de Lausanne (EPFL), Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques, Laboratoire des Polymères, Bâtiment MXD, Station 12, CH-1015 Lausanne.

Chimia
|October 27, 2011
PubMed
Summary
This summary is machine-generated.

Polymer chemistry advances enable precise modification of peptides and proteins. These techniques create advanced materials for regenerative medicine, diagnostics, and polymer therapeutics.

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Chemical Biology

Background:

  • Controlled radical polymerization (CRP) and site-specific bioconjugation are key for polymer-based biomaterials.
  • These methods allow for precise modification of peptides and proteins with synthetic polymers.
  • This integration addresses challenges at the biology-materials interface.

Purpose of the Study:

  • To review recent advancements in polymer chemistry for biological applications.
  • To highlight the use of CRP and bioconjugation in developing bioactive surfaces and polymer therapeutics.
  • To showcase applications in regenerative medicine, diagnostics, and nanomedicine.

Main Methods:

  • Controlled radical polymerization techniques for polymer synthesis.
  • Site- and residue-specific strategies for peptide/protein modification.
  • Development of polymer-based coatings and nanomedicines.

Main Results:

  • Successful creation of bioactive surface modifications using polymer chemistry.
  • Development of polymer therapeutics with tailored properties.
  • Demonstration of polymer-based nanomedicines for therapeutic applications.

Conclusions:

  • Polymer chemistry offers powerful tools for addressing biological interface challenges.
  • CRP and bioconjugation are essential for developing advanced biomaterials.
  • Future applications include enhanced regenerative medicine, diagnostics, and nanomedicine.