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Updated: May 28, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
Published on: February 25, 2011
Preparation of translationally cold neutral molecules
Giulia Di Domenicantonio1, Benjamin Bertsche, Andreas Osterwalder
1Institut des Sciences et Ingénierie Chimiques, EPFL-SB, CH-1015-Lausanne.
Abstract:
Efforts at EPFL to obtain translationally cold neutral molecules are described. Active deceleration of polar molecules is performed by confining the molecules in moving three-dimensional electrostatic traps, and by appropriately choosing the velocity of those traps. Alternatively, cold molecules can be obtained by velocity filtering. Here, the velocity of the molecules is not changed, but instead the cold molecules are extracted from a thermal sample by using the competition between the electrostatic force and the centrifugal force inside a bent electrostatic guide for polar molecules.
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