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Updated: May 28, 2026

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Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Published on: October 29, 2021
Affected upper-extremity movement ability is retained 3 months after modified constraint-induced therapy
Stephen J Page1, Colleen Murray, Valerie Hermann
1School of Allied Medical Professions, Division of Occupational Therapy, The Ohio State University, 406 Atwell Hall, 453 West Tenth Avenue, Columbus, OH 43210, USA. page.61@osu.edu
Summary
Modified constraint-induced therapy (mCIT) shows sustained upper-extremity motor improvements 3 months post-intervention. This outpatient therapy encourages habitual limb use, leading to lasting gains for stroke patients.
Area of Science:
- Neurorehabilitation
- Stroke Recovery
- Physical Therapy
Background:
- Constraint-induced movement therapy (CIT) faces limitations in clinical practicality and patient adherence.
- Outpatient, modified constraint-induced therapy (mCIT) has demonstrated efficacy over the past decade.
- Sustained motor improvements after mCIT intervention require further investigation.
Purpose of the Study:
- To determine if motor gains achieved through mCIT are retained 3 months after the intervention concludes.
- To assess the long-term effects of mCIT on upper-extremity motor function in post-stroke patients.
Main Methods:
- A prospective study tracked 13 post-stroke participants.
- Upper-extremity motor function was assessed using the Fugl-Meyer Impairment Scale (FM) and the Action Research Arm Test (ARA).
- Assessments were conducted immediately after the 10-week mCIT intervention and again 3 months later.
Main Results:
- Significant increases in upper-extremity motor function were observed between the post-intervention assessment and the 3-month follow-up.
- 25 out of 26 scores on the FM and ARA demonstrated improvement.
- Participants showed continued gains in affected extremity movement ability 3 months after completing mCIT.
Conclusions:
- mCIT promotes sustained motor improvements in post-stroke individuals.
- The extended period of increased extremity-use opportunities during mCIT may foster habitual use, leading to lasting functional gains.
- mCIT offers a practical and effective approach for long-term upper-extremity rehabilitation in stroke survivors.

