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Updated: May 28, 2026
08:49
External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
[Cervical pregnancy can be managed conservatively with methotrexate]
Marie Sørensen1, Helle Vibeke Clausen
1Gynækologisk Obstetrisk Afdeling, Hillerød Hospital, 3400 Hillerød, Denmark. sorensenmarie@hotmail.com
Ugeskrift for Laeger
|October 27, 2011
Summary
Conservative management of cervical ectopic pregnancy after in vitro fertilization embryo transfer using methotrexate is effective. Both cases, one living and one with a fetal pole, showed stability during treatment, indicating successful outcomes with this approach.
Area of Science:
- Reproductive Medicine
- Gynecologic Surgery
- Pharmacology
Background:
- Cervical ectopic pregnancy is a rare complication following in vitro fertilization (IVF) embryo transfer.
- Conservative management strategies are being explored for these challenging cases.
Observation:
- Two patients with cervical ectopic pregnancy post-IVF embryo transfer were managed conservatively.
- One case involved a living cervical ectopic pregnancy, the other a fetal pole.
Findings:
- The living cervical ectopic pregnancy received intra-amniotic and systemic methotrexate, maintaining stable vital signs.
- The cervical ectopic pregnancy with a fetal pole, initially presenting with bleeding and anemia, was treated with systemic methotrexate after stabilization and remained stable.
Implications:
- Conservative management with methotrexate appears to be a viable and effective treatment for cervical ectopic pregnancy after IVF.
- This approach offers a less invasive alternative to surgical intervention in select cases.
- Further research can explore optimal methotrexate dosing and administration routes for improved outcomes.
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