Interfacing living yeast cells with graphene oxide nanosheaths
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Updated: May 28, 2026

Graphene Enclosure of Chemically Fixed Mammalian Cells for Liquid-Phase Electron Microscopy
Published on: September 21, 2020
Sung Ho Yang1, Taemin Lee, Eunyong Seo
1Molecular-Level Interface Research Center, Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
Abstract:
The first example of the encapsulation of living yeast cells with multilayers of GO nanosheets via LbL self-assembly is reported. The GO nanosheets with opposite charges are alternatively coated onto the individual yeast cells while preserving the viability of the yeast cells, thus affording a means of interfacing graphene with living yeast cells. This approach is expanded by integrating other organic polymers or inorganic nanoparticles to the cells by hybridizing the entries with GO nanosheets through LbL self-assembly. It is demonstrated that incorporated iron oxide nanoparticles can deliver magnetic properties to the biological systems, allowing the integration of new physical and chemical functions for living cells with a combination of GO nanosheets.

