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Updated: May 28, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
09:17

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness

Published on: May 2, 2017

[Nutrition in the critically ill].

A Weimann1, J Andrä, A Sablotzki

  • 1Klinikum St. Georg gGmbH Leipzig. Arved.Weimann@sanktgeorg.de

Deutsche Medizinische Wochenschrift (1946)
|October 27, 2011
PubMed
Summary
This summary is machine-generated.

Malnourished intensive care patients need adequate energy and protein. Early enteral nutrition is beneficial, but gastrointestinal intolerance poses challenges, necessitating guideline-based protocols for optimal nutritional support.

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Last Updated: May 28, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
09:17

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness

Published on: May 2, 2017

Area of Science:

  • Clinical Nutrition
  • Intensive Care Medicine
  • Gastroenterology

Background:

  • The critical role of nutritional support in intensive care unit (ICU) patients is well-established.
  • Early enteral nutrition is generally recommended for critically ill patients to improve outcomes.
  • However, gastrointestinal intolerance can impede the delivery of adequate enteral nutrition.

Observation:

  • Malnourished ICU patients face significant risks from inadequate energy and protein intake.
  • Gastrointestinal intolerance is a common complication that limits the effectiveness of enteral nutrition.
  • There is ongoing debate regarding the optimal timing for initiating total parenteral nutrition (TPN) or combined nutrition when enteral feeding is insufficient.

Findings:

  • Immune-enhancing substrates require cautious administration due to potential adverse effects.
  • Implementing guideline-based nutritional protocols is recommended for standardization of care.
  • Recent guidelines from European, American, and German societies offer recommendations for nutritional management in critically ill patients.

Implications:

  • Standardized nutritional protocols can improve the feasibility and safety of nutritional support in ICUs.
  • Addressing gastrointestinal intolerance is crucial for successful enteral feeding.
  • Further research may clarify the optimal use of TPN and specialized substrates in complex critical care nutrition scenarios.