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Langerhans cell histiocytosis.

D R Aruna1, G Pushpalatha, Sushma Galgali

  • 1Department of Periodontics, VokkaligaraSangha Dental College and Hospital, Bangalore, India.

Journal of Indian Society of Periodontology
|October 27, 2011
PubMed
Summary

Langerhans cell histiocytosis (LCH) is a rare disease involving Langerhans cell proliferation. This case highlights rare oral soft tissue lesions without bone involvement in a young woman.

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Area of Science:

  • Histiocytosis and proliferative disorders.
  • Rare diseases and their clinical manifestations.

Background:

  • Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder.
  • LCH typically involves bone, but can affect multiple organs including lungs, liver, lymph nodes, skin, and mucosa.

Observation:

  • Oral soft tissue lesions are an uncommon presentation of LCH.
  • This report details a case of LCH presenting with oral soft tissue lesions without bone involvement.

Findings:

  • The study focuses on a rare presentation of Langerhans cell histiocytosis.
  • The case involves a young woman with oral soft tissue lesions as the primary manifestation.

Implications:

  • Understanding rare presentations of LCH is crucial for timely diagnosis.
Keywords:
CD1a glycoproteinLangerhans cell histiocytosiscytoplasmatic protein S100immunohistochemistryperiodontitis

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  • This case broadens the spectrum of known LCH manifestations, emphasizing oral tissues.