Related Experiment Video
Updated: May 28, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Congenital syphilis presenting with a generalized bullous and pustular eruption in a premature newborn
Jin Ki Kim1, Se Rim Choi, Hee Jung Lee
1Department of Dermatology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Abstract:
Congenital syphilis occurs when Treponema pallidum crosses the placenta during pregnancy or from contact with an infectious genital lesion during delivery. Cutaneous manifestations of congenital syphilis are relatively common, occurring in approximately 30% to 70% of patients. Maculopapular lesions, vesiculobullous lesions, condylomata lata lesions, annular lesions, and erythema multiforme-like targetoid lesions have been reported. We report on a premature newborn with congenital syphilis who presented with generalized bullous and pustular eruption and desquamation at birth.
Related Concept Videos
Sexually Transmitted Infections
Bacterial Meningitis I: Introduction
Staphylococcal Skin Infections
Smallpox
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Rocky Mountain Spotted Fever
