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Peptide-based Identification of Functional Motifs and their Binding Partners
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Published on: June 30, 2013

Human immunodeficiency virus endocrinopathy.

Uma Sinha1, Nilanjan Sengupta, Prasanta Mukhopadhyay

  • 1Department of Medicine, Nilratan Sircar Medical College and Hospital, Kolkata, India.

Indian Journal of Endocrinology and Metabolism
|October 27, 2011
PubMed
Summary
This summary is machine-generated.

Human immunodeficiency virus (HIV) infection impacts nearly all endocrine organs, causing various disorders. Early evaluation and treatment of HIV endocrinopathy can improve patient quality of life and survival.

Keywords:
Antiretroviral therapyendocrinopathyhuman immunodeficiency viruslipodystrophywasting

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Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Virology

Background:

  • Human immunodeficiency virus (HIV) infection affects virtually all endocrine organs.
  • Endocrine dysfunction in HIV can be direct or secondary to opportunistic infections and neoplasms.
  • HIV infection involves complex interactions with the endocrine system, leading to hormonal imbalances.

Purpose of the Study:

  • To provide a comprehensive overview of HIV endocrinopathy.
  • To highlight the spectrum of endocrine disorders associated with HIV.
  • To emphasize the importance of endocrinal evaluation and management in HIV patients.

Main Methods:

  • Literature review of HIV endocrinopathy.
  • Analysis of endocrine manifestations in immunocompromised states.
  • Discussion of treatment implications for quality of life and mortality.

Main Results:

  • HIV can directly impair glandular function or cause secondary dysfunction.
  • Common endocrine issues include adrenal insufficiency, hypogonadism, diabetes, and bone loss.
  • AIDS wasting syndrome and HIV lipodystrophy are significant concerns.

Conclusions:

  • Endocrine evaluation in HIV patients should follow standard protocols.
  • Antiretroviral therapy and other medications can have adverse endocrinal effects.
  • Effective management of HIV endocrinopathy improves quality of life and long-term outcomes.