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Updated: May 28, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Ultrahigh resolution all-reflective optical coherence tomography system with a compact fiber-based supercontinuum
Khanh Quoc Kieu1, Justin Klein, Anna Evans
1University of Arizona, College of Optical Sciences, Optical Sciences Meinel Building, 1630 E. University Boulevard, Tucson, Arizona 85721, USA. kkieu@optics.arizona.edu
We developed an all-reflective optical coherence tomography (OCT) system for ultrahigh-resolution imaging. This new system avoids dispersion and achieves 2 μm axial resolution, enabling detailed biological sample visualization.
Area of Science:
- Biomedical optics
- Optical imaging technologies
- Advanced microscopy
Background:
- Chromatic dispersion limits resolution in traditional optical coherence tomography (OCT) systems.
- Achieving ultrahigh resolution in OCT is crucial for detailed biological sample analysis.
- Supercontinuum sources offer broad bandwidths for enhanced OCT performance.
Purpose of the Study:
- To construct and characterize an all-reflective OCT system.
- To leverage a novel fiber-based supercontinuum source for improved imaging.
- To overcome chromatic dispersion limitations for ultrahigh-resolution OCT.
Main Methods:
- Utilized an all-reflective optical design to eliminate chromatic dispersion.
- Integrated a compact fiber-based broadband supercontinuum source.
- Characterized the system's axial resolution and dynamic range.
Main Results:
- Achieved an axial resolution of 2 μm in air.
- Demonstrated an 87 dB dynamic range.
- Acquired ultrahigh-resolution OCT images of biological samples at 1300 nm.
Conclusions:
- The all-reflective OCT system effectively eliminates chromatic dispersion.
- The developed system provides ultrahigh resolution for biological imaging.
- This technology advances the capabilities of optical coherence tomography.
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